Decreased Head Circumference Velocity as Related to Developmental Deficit in Infancy

作者：Tal Galit; Cohen Ayala; Habib Sonia; Tirosh Emanuel^*

来源：Pediatric Neurology, 2012, 47(5): 341-344.

DOI：10.1016/j.pediatrneurol.2012.07.002

We evaluated the significance of head circumference growth velocity as related to developmental deficits during infancy. Head circumferences, lengths, and developmental diagnoses were retrieved in a standard manner at %26gt;= 2 time points from 437 infants with developmental deficits, and 3909 normally developing infants. Infants%26apos; ages ranged from 1-24 months, with final diagnoses ascertained at age 24 months. Increased velocity during the first 2 months in typical infants was evident in the study group during the period 2-4 months. A differential head circumference growth velocity was observed, and infants diagnosed with motor delay presented decreased velocity between ages 2-4 months, compared with infants receiving other nonmotor developmental diagnoses. These differences remained after controlling for birth weight and length. No significant sex effect was evident. Infants with developmental deficits demonstrate delayed acceleration of head circumference velocity, compared with typical infants in the first 2 months. Infants with motor delay manifest decreased velocity, compared with infants presenting other developmental deficits. These differences may be related to delayed white matter maturation.

• 出版日期2012-11