[Hmim]TFA catalyzed multicomponent reaction: direct, mild, and efficient procedure for the synthesis of 1,2-dihydroquinazoline derivatives

作者：Dabiri Minoo^*; Bahramnejad Mahboobeh; Bashiribod Sahareh

来源：Molecular Diversity, 2010, 14(3): 507-512.

DOI：10.1007/s11030-009-9219-8

• Multicomponent reaction
• 1,2-Dihydroquinazolines
• Ionic liquid

4-Substituted-spiro-1,2-dihydroquinazolines and related compounds were synthesized by direct reaction of 2-aminobenzophenones, isatin, or 1,2-diketone derivatives and ammonium acetate in the presence of dual role catalyst-solvent ionic liquid, [Hmim]TFA. Excellent conversion of starting materials was achieved to the desired 1,2-dihydroquinazoline products.

• 出版日期2010-8