A concerted decline in insulin secretion and action occurs across the spectrum of fasting and postchallenge glucose concentrations

作者：Sathananthan Airani; Dalla Man Chiara; Zinsmeister Alan R; Camilleri Michael; Rodeheffer Richard J; Toffolo Gianna; Cobelli Claudio; Rizza Robert A; Vella Adrian^*

来源：Clinical Endocrinology, 2012, 76(2): 212-219.

DOI：10.1111/j.1365-2265.2011.04159.x

Aims/hypothesis Individuals with impaired fasting glucose (IFG) are at increased risk of developing diabetes over the subsequent decade. However, there is uncertainty as to the mechanisms contributing to the development of diabetes. We sought to quantitate insulin secretion and action across the prediabetic range of fasting glucose.

• 出版日期2012-2