A novel and practical synthesis of 2-benzoylbenzothiazoles and 2-benzylbenzothiazoles

作者：Fan, Xuesen^*; He, Yan; Wang, Yangyang; Xue, Zaikun; Zhang, Xinying; Wang, Jianji

来源：Tetrahedron Letters, 2011, 52(8): 899-902.

DOI：10.1016/j.tetlet.2010.12.057

• SUBSTITUTED PROPARGYLIC ALCOHOLS
• ALPHA-KETO HETEROCYCLES
• ONE-STEP SYNTHESIS
• 2-SUBSTITUTED BENZOTHIAZOLES
• MICROWAVE IRRADIATION
• EFFICIENT SYNTHESIS
• BIOLOGICAL EVALUATION
• IONIC LIQUIDS
• IRON
• OXIDATION

A novel methodology for the synthesis of 2-benzoylbenzothiazoles and 2-benzylbenzothiazoles through FeCl3 center dot 6H(2)O catalyzed, air oxidized tandem process from commercially available 2-aminothiophenols and phenylacetaldehydes by using an ionic liquid as both reaction medium and co-catalyst was developed.

• 出版日期2011-2-23
• 单位河南师范大学