A facile strategy for the synthesis of highly substituted imidazole using tetrabutyl ammoniumbromide as catalyst

作者：Kurumurthy C; Kumar G Santhosh; Reddy G Malla; Nagender P; Rao P Shanthan; Narsaiah B^*

来源：Research on Chemical Intermediates, 2012, 38(2): 359-365.

DOI：10.1007/s11164-011-0352-5

• 1,2-Diketone
• Aldehyde
• Amine
• Multi-component condensation
• Tetrabutyl ammonium bromide
• Ammonium acetate/ammonium formate

A simple and facile strategy for the synthesis of highly substituted imidazoles has been developed by multi-component condensation of 1,2-diketone, aldehyde, amine, and ammonium acetate in presence of tetrabutyl ammonium bromide as catalyst.

• 出版日期2012-2