Upper abdominal procedures in advanced stage ovarian or primary peritoneal carcinoma patients with minimal or no gross residual disease: An analysis of Gynecologic Oncology Group (GOG) 182

作者：Rodriguez Noah; Miller Austin; Richard Scott D; Rungruang Bunja; Hamilton Chad A; Bookman Michael A; Maxwell G Larry; Horowitz Neil S; Krivak Thomas C^*

来源：Gynecologic Oncology, 2013, 130(3): 487-492.

DOI：10.1016/j.ygyno.2013.06.017

• Ovarian cancer
• Upper abdominal procedures
• Surgical debulking

Purpose. To examine the utility of upper abdominal procedures (UAPs) performed in a cohort of optimally cytoreduced patients with advanced stage epithelial ovarian cancer (EOC) or primary peritoneal cancer (PPC) and identify potential areas where aggressive surgery may impact survival.
Patients and methods. We reviewed 2655 patients enrolled in Gynecologic Oncology Group (GOG) 182 who had complete resection (CR) or minimal residual (MR) disease <1 cm. Demographic, pathologic, surgical, and outcome data were collected. UAPs included diaphragm stripping or resection, liver resection, splenectomy, pancreatectomy, and porta hepatis surgery. Effect of UAP and CR on PFS/OS was assessed by Kaplan-Meier and proportional hazards methods.

• 出版日期2013-9