Antioxidant activities of new flavonoids from Cudrania tricuspidata root bark

作者：Lee Young Jae; Kim Sungun; Lee Seung Jae; Ham Inhye; Whang Wan Kyunn^*

来源：Archives of Pharmacal Research, 2009, 32(2): 195-200.

DOI：10.1007/s12272-009-1135-z

• Cudrania tricuspidata (Moraceae)
• 6-p-Hydroxybenzyl kaempferol-7-O-beta-D-glucopyranoside (cudranian 1)
• 6-p-Hydroxybenzyl quercetin-7-O-beta-D-glucopyranoside (cudranian 2)
• Anti-oxidative activity

Two new flavonoids, hydroxybenzyl flavonoid glycosides (6-p-hydroxybenzyl kaempferol-7-O-beta-D-glucopyranoside named cudranian 1 and 6-p-hydroxybenzyl quercetin-7-O-beta-D-glucopyranoside named cudranian 2), and 3 known flavonoids (kaempferol-7-O-beta-D-glucopyranoside, quercetin-7-O-beta-D-glucopyranoside and aromadendrin) were isolated from root bark of Cudrania tricuspidata and their structures were elucidated by spectroscopic methods. These compounds showed remarkable radical scavenging effects against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and anti-lipid peroxidation efficacy on human low-density lipoprotein by TBARS assay.

• 出版日期2009-2