Contact Lens-induced Limbal Stem Cell Deficiency

作者：Rossen Jennifer; Amram Alec; Milani Behrad; Park Dongwook; Harthan Jennifer; Joslin Charlotte; McMahon Timothy; Djalilian Ali^*

来源：Ocular Surface, 2016, 14(4): 419-434.

DOI：10.1016/j.jtos.2016.06.003

• corneal conjunctivalization
• contact lens
• limbal stem cell deficiency
• limbal stem cells

Limbal stem cell deficiency (LSCD) is a pathologic condition caused by the dysfunction and/or destruction of stem cell precursors of the corneal epithelium, typified clinically by corneal conjunctivalization. The purpose of this review is to critically discuss a less well-known cause of limbal stem cell disease: contact lens (CL) wear. A literature search was conducted to include original articles containing patients with CL-induced LSCD. This review describes epidemiology, diagnostic strategies, pathogenesis, differential diagnosis, and treatment modalities for this condition.

• 出版日期2016-10