The Role of Biopsy in Pediatric Dermatopathology

作者：Afsar Fatma Sule^*; Aktas Safiye; Diniz Gulden; Ortac Ragip

来源：Turkderm-Archives of the Turkish Dermatology and Venerology, 2011, 45(3): 137-139.

DOI：10.4274/turkderm.87894

• Paediatric
• dermatopathology
• biopsy
• clinicopathologic correlation

Background and Design: Pediatric dermatology is characterized by skin disorders which have frequencies different from those in adults. Skin biopsies are necessary for differential diagnosis and clinicopathologic correlation is very important. The aim of this study was to evaluate retrospectively the pediatric dermatology cases in whom biopsy was performed for differential diagnosis and to investigate the contribution of biopsy to diagnosis of skin disorders.
Material and Methods: The cases from whom biopsy was taken in the pediatric dermatology clinic during a three-year period were evaluated retrospectively for pre-diagnoses, biopsy diagnoses, and success of biopsies.
Results: Two hundred thirteen (1.7%) skin biopsies had been taken from a total of 12420 patients. Henoch-Schonlein purpura, psoriasis, pityriasis lichenoides, pityriasis rosea, lichen planus, pityriasis rubra pilaris, erythema multiforme, atopic dermatitis, granuloma annulare, and pigmented purpuric dermatosis were the most frequent skin disorders diagnosed dermatopathologically. In a total of 120 (56.3%) cases, the biopsy diagnosis was within the pre-diagnosis and a biopsy consistency was present. In 25 (11.7%) cases, biopsy had no contribution to the differential diagnosis. An absolutely different diagnosis which was incompatible with the pre-diagnosis had been reported in 10 (4.6%) cases.
Conclusion: In pediatric dermatology, skin biopsy is very helpful for the differential diagnosis. An easy biopsy procedure for the patient, an effective designation of biopsy indication, a good dermatopathologic correlation and an experienced team of pediatric dermatopathology increase the success of skin biopsies. (Turkderm 2011; 45: 137-9)

• 出版日期2011-9