Dimethyl Sulfoxide/Potassium Hydroxide: A Superbase for the Transition Metal-Free Preparation of Cross-Coupling Products

作者：Yuan Yu; Thome Isabelle; Kim Seok Hwan; Chen Duanteng; Beyer Astrid; Bonnamour Julien; Zuidema Erik; Chang Sukbok; Bolm Carsten

来源：Advanced Synthesis & Catalysis, 2010, 352(17): 2892-2898.

DOI：10.1002/adsc.201000575

• arylation
• catalysis
• cross-coupling
• dimethyl sulfoxide/potassium hydroxide (DMSO/KOH)
• superbase
• transition metal-free conditions

Potassium hydroxide (KOH) in dimethyl sulfoxide (DMSO) forms a superbasic medium that allows one to access cross-coupling products from reactions between aryl halides with various sulfur-, oxygen- and nitrogen-based nucleophiles under transition metal-free conditions.

• 出版日期2010-11-22
• 单位扬州大学