Age, sex, and secondary prevention of ischaemic heart disease in everyday practice

作者:Jankowski Piotr*; Czarnecka Danuta; Wolfshaut Wolak Renata; Lysek Radoslaw; Lukaszewska Anna; Surowiec Slawomir; Loster Magdalena; Bogacki Piotr; Bryniarska Mirek Ewa; Grodecki Janusz; Nessler Jadwiga; Podolec Piotr; Kawecka Jaszcz Kalina; Pajak Andrzej
来源:Kardiologia Polska, 2013, 71(12): 1251-1259.
DOI:10.5603/KP.a2013.0148

摘要

Background: Many researchers have studied age-and sex-related differences in the management of patients with coronary artery disease. However, the results are inconsistent. %26lt;br%26gt;Aim: To assess sex-and age-related bias in the secondary prevention in patients hospitalised due to ischaemic heart disease. %26lt;br%26gt;Methods: Five hospitals with departments of cardiology serving a city and surrounding districts in southern Poland participated in the study. Consecutive patients hospitalised from 1 April 2005 to 31 July 2006 due to acute coronary syndrome or for a myocardial revascularisation procedure and aged %26lt;= 80 years were recruited and interviewed 6-18 months after hospitalisation. %26lt;br%26gt;Results: The hospital records of 640 patients were reviewed and 513 (80.2%) patients participated in the follow-up interview. Women were older and less educated than their male counterparts. Sex was not independently associated with the control of major risk factors in the post-discharge period, whereas age was related to a higher probability of having high blood pressure and a lower chance of smoking. Multivariate analysis showed that females were prescribed calcium antagonists (odds ratio [OR] 2.13; 95% confidence intervals [CI] 1.34-3.39) and diuretics (OR 1.52; 95% CI 1.00-2.31) more often than males. Age was independently related to the prescription rate of diuretics (%26gt;= 70 years vs. %26lt; 60 years; OR 1.61; 95% CI 1.19-2.20). The prescription rate of antiplatelets, beta-blockers, angiotensin converting enzyme-inhibitors/sartans, lipid-lowering drugs, and anticoagulants was not related to age or sex. %26lt;br%26gt;Conclusions: We found no major sex-related difference in the frequency of achieving recommended goals in secondary prevention, whereas age was related to a lower prevalence of smoking and a higher probability of having high blood pressure in subjects after hospitalisation for coronary artery disease.

  • 出版日期2013