Scavenger receptor class B1-a target to reduce CHD risk?

作者:Barter Philip J*; Rye Kerry Anne
来源:Nature Reviews Cardiology, 2016, 13(5): 249-250.
DOI:10.1038/nrcardio.2016.50

摘要

A loss-of-function mutation in the gene encoding scavenger receptor classB member 1 (SRB1) has been identified. This mutation increases the risk of coronary heart disease (CHD) despite being associated with increased concentration of HDL cholesterol. Upregulation of SRB1 expression might be a novel therapeutic approach for reducing CHD risk.

  • 出版日期2016-5

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