An elegant one-pot synthesis of isoxazolo[2,3-a]pyrimidines

作者：Rajanarendar E^*; Raju S; Reddy M Nagi; Murthy K Rama

来源：Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry , 2010, 49(10): 1422-1427.

• One-pot synthesis
• 3-amino-5-methylisoxazole
• 4-arylidene-2-phenyl-5-oxazolone
• chalcone
• isoxazolo[2,3-a]pyrimidines

An elegant one-pot synthesis of isoxazolo[2,3-a]pyrimidines has been achieved by reaction of 3-amino-5-methylisoxazole with 4-arylidene-2-phenyl-5-oxazolones. Treatment of 3-amino-5-methylisoxazole with chalconcs also resulted in the formation of isoxazolo[2,3-a]pyrimidines in a single step. The structure of the products have been elucidated by spectral and analytical data.

• 出版日期2010-10