A heme degradation enzyme, HutZ, from Vibrio cholerae

作者：Uchida Takeshi^*; Sekine Yukari; Matsui Toshitaka; Ikeda Saito Masao; Ishimori Koichiro

来源：Chemical Communications, 2012, 48(53): 6741-6743.

DOI：10.1039/c2cc31147j

HutZ, one of the crucial proteins of the iron uptake system in Vibrio cholerae, was purified, which binds to heme at a stoichiometry of 1 : 1. In the presence of ascorbic acid, the HutZ-bound heme degrades via the same intermediates observed in heme oxygenase, suggesting that HutZ works as a heme degradation enzyme.

• 出版日期2012