Nitrogen doped graphene supported Pt-Pd nanoparticle modified GC electrode for electrochemical determination of tramadol and paracetamol

作者：Manokaran Janakiraman; Narendranath Jonna; Muruganantham Rethinasabapathy; Balasubramanian Natesan^*

来源：Indian Journal of Chemistry - Section A: Inorganic, Physical, Theoretical and Analytical Chemistry , 2017, 56(1): 63-68.

• Electrochemistry
• Electroanalysis
• Graphene
• Doped graphene
• Electrodes
• Modified electrodes
• Paracetamol
• Tramadol

The role of functionalized nitrogen doped graphene (NGp) using poly(diallyldimethylammonium chloride) (PDDA) as modified electrode has been discussed. Pt-Pd bimetallic nanoparticles have been anchored on PDDA-NGp to form PtPd-PDDA-NGp nanocomposites, which are characterized by high resolution transmission electron microscope, X-ray diffraction and Raman spectroscopy. The simultaneous determination of paracetamol and tramadol has been carried out using the nitrogen doped graphene supported Pt-Pd nanoparticle modified glassy carbon electrode in 0.1 M Britton-Robinson buffer solution (pH 5.0). Two well-defined voltammetric peaks are obtained in square wave voltammogram measurements. It has been observed that the modified electrode can detect a wide linear range of concentrations of paracetamol from 5x10(-6) to 1x10(-4) M, and tramadol from 1.2x10(-5) to 2.4x10(-4) M. The limit of detection was found to be 1.8x10(-7) and 5.7x10(-6) M for paracetamol and tramadol, respectively (S/N = 3).

• 出版日期2017-1