A HER 1-2 Punch: Dual EGFR Targeting Deals Resistance a Deadly Blow

作者:Gibbons Don L; Byers Lauren Averett*
来源:Cancer Discovery, 2014, 4(9): 991-994.
DOI:10.1158/2159-8290.CD-14-0791

摘要

Ten years after the approval of erlotinib, EGFR inhibitor resistance remains a major clinical challenge. The translation of afatinib plus cetuximab into the clinic provides a promising new option for the treatment of patients with EGFR-mutated lung cancer.

  • 出版日期2014-9