A Population-Based Study on Myelodysplastic Syndromes in the Lazio Region (Italy), Medical Miscoding and 11-Year Mortality Follow-Up: the Gruppo Romano-Laziale Mielodisplasie Experience of Retrospective Multicentric Registry

作者：Mayer Flavia; Faglioni Laura; Agabiti Nera; Fenu Susanna; Buccisano Francesco; Latagliata Roberto; Ricci Roberto; Spiriti Maria Antonietta Aloe; Tatarelli Caterina; Breccia Massimo; Cimino Giuseppe; Fianchi Luana; Criscuolo Marianna; Gumenyuk Svitlana; Mancini Stefano; Maurillo Luca; Nobile Carolina; Niscola Pasquale; Piccioni Anna Lina; Tafuri Agostino; Trape Giulio; Andriani Alessandro; De Fabritiis Paolo; Voso Maria Teresa; Davoli Marina; Zini Gina

来源：Mediterranean Journal of Hematology and Infectious Diseases, 2017, 9(1): e2017046.

DOI：10.4084/MJHID.2017.046

<jats:p>Results on myelodysplastic syndromes (MDS) from population-based studies are rare and these data are infrequently collected by cancer registries because diagnostic difficulties and under-reported data.Our is the first regional Lazio study about medical coding, diagnosis, classification and mortality of MDS patients. This study is aimed at evaluating MDS medical miscoding and conducting a mortality follow-up in a cohort of 644 MDS patients enrolled in the Gruppo Romano-Laziale Mielodisplasie (GROM-L) registry from 2002 to 2010.We linked the MDS cohort with 2 regional health information systems: the Hospital Information System (HIS) and the regional Mortality Information System (MIS).About the first objective 92% of the patients had at most 12 hospitalization, but 28.5% of them had no hospitalization with the 238.7 ICD-9-CM. About the second objective we observed 45.5% of death during the follow-up, Myelodysplastic Syndrome was the second cause of death, other frequent causes of death were myeloid leukemia and aplastic anemia.This study highlights for the first time in Lazio that a disease like MDS, involving many resources for care assistance, tends to be under-documented in the HIS archive. This may be due to the evolution of the disease over the time, the inappropriate use of existing ICD-9-CM and the limitations of current ICD-9-CM classification. Moreover, the most frequent causes of death other than MDS might suggest a miscoding of MDS in the death causes too.In conclusion our registry could be a useful investigational tool to make a continued surveillance on medical miscoding and collect epidemiological data.</jats:p>

• 出版日期2017-7-1