Diethylenetriamine-Mediated Direct Cleavage of Unactivated Carbamates and Ureas

作者:Noshita Megumi; Shimizu Yuhei; Morimoto Hiroyuki; Ohshima Takashi
来源:Organic Letters, 2016, 18(23): 6062-6065.
DOI:10.1021/acs.orglett.6b03016

摘要

Diethylenetriamine is effective for the direct cleavage of unactivated carbamates and ureas without additional reagents and catalysts. Various carbamates and ureas were cleaved to afford products in good yield, and the reactions were not affected by air or moisture. Unique chemoselective cleavage of carbamate and urea in the presence of amides was also achieved.

  • 出版日期2016-12-2