An efficient and one pot synthesis of polysubstituted imidazoles catalyzed by BiCl3

作者：Sharma R K^*; Sharma Chetna; Prerna

来源：Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry , 2012, 51(10): 1489-1493.

• Multicomponent reaction
• one-pot synthesis
• 2,4,5-trisubstituted imidazoles
• 1,2, 4,5-tetrasubstituted imidazoles

BiCl3 has been found to be a mild and effective catalyst for the efficient, one-pot, three component synthesis of 2,4,5-trisubstituted imidazoles at RT. Moreover, the utility of this protocol has further been explored conveniently for the one-pot, four component synthesis of 1,2,4,5-tetrasubstituted imidazoles in high yields.

• 出版日期2012-10