A modular zinc finger adaptor accelerates the covalent linkage of proteins at specific locations on DNA nanoscaffolds

作者:Nakata Eiji; Dinh Huyen; Ngo Tien Anh; Saimura Masayuki; Morii Takashi*
来源:Chemical communications, 2015, 51(6): 1016-1019.
DOI:10.1039/c4cc08167f

摘要

A modular adaptor consisting of a sequence-specific DNA binding zinc finger protein and a self-ligating protein-tag was developed to expedite efficient formation of a covalent linkage between an individual protein molecule and the programmed address modified with a tag-substrate on the DNA nanostructure.

  • 出版日期2015