Alfentanil anesthetic augmentation lengthens seizure duration in electroconvulsive therapy with older people

作者：D'Cunha Craig^*; Plakiotis Christos; O'Connor Daniel W

来源：International Psychogeriatrics, 2016, 28(6): 1051-1052.

DOI：10.1017/S1041610216000119

<jats:p>Electroconvulsive therapy (ECT) prescription rates rise with age, making it important that treatments be made as effective and safe as possible (Plakiotis<jats:italic>et al.</jats:italic>, 2012). Older people are vulnerable to post-treatment confusion and to subsequent deficits in attention, new learning, and autobiographical memory (Gardner and O'Connor, 2008). Strategies to minimize cognitive side-effects include unilateral electrode placement and stimulus dose titration whereby electrical charge is individually calibrated to seizure threshold (Sackeim<jats:italic>et al</jats:italic>., 2000). It remains the case, however, that threshold levels typically rise over the treatment course, leading to an increase both in delivered charge and the risk of adverse sequelae.</jats:p>

• 出版日期2016-6