A one-pot multi-component reaction for the facile synthesis of some novel 2-aryl thiazolidinones bearing benzimidazole moiety using La(NO3)(3)center dot 6H(2)O as an efficient catalyst

作者：Kalhor Mehdi^*; Banibairami Soodabeh; Mirshokraie Seyed Ahmad

来源：Research on Chemical Intermediates, 2017, 43(11): 5985-5994.

DOI：10.1007/s11164-017-2974-8

• Synthesis
• Multi-component reaction
• Catalyst
• Lanthanum nitrate hexahydrate
• 1,3-thiazolidinone
• 2-aminobenzimidazole

A series of new derivatives of 3-benzimidazolyl-2-aryl thiazolidinones, 4a-j are synthesized via a rapid, one-pot, three-component reaction by using La(NO3)(3)center dot 6H(2)O as an efficient catalyst from the reaction of 2-aminobenzimidazole, aromatic aldehydes and thioglycolic acid in ethanol at room temperature. These new compounds were characterized by IR, H-1, C-13 NMR and mass spectroscopies. An inexpensive and available catalyst, short reaction time, easy workup, good to excellent yields and nontoxic solvent are the advantages of this reaction.

• 出版日期2017-11