A new isoprenyl phenyl ether compound from mangrove fungus

作者：Shao, Changlun; Guo, Zhiyong; Peng, Hong; Peng, Guangtian; Huang, Zhongjing; She, Zhigang; Lin, Yongcheng^*; Zhou, Shining

来源：Chemistry of Natural Compounds, 2007, 43(4): 377-379.

DOI：10.1007/s10600-007-0142-x

• marine fungi
• biological activity
• isoprenyl phenyl ether

A new isoprenyl phenyl ether, 3-hydroxy-4-(3-methylbut-2-enyloxy)benzoic acid methyl ester (1), together with 4-hydroxybenzoic acid (2), 2-hydroxy-6-methylbenzoic acid (3), and 4-hydroxy-3-methoxybenzoic acid (4) were isolated from Mangrove fungus (No. B60) from the South China Sea. The structures of the compounds were established on the basis of NMR spectroscopic and mass spectrometric data. In the preliminary bioassay, compound 1 exhibited antibacterial and antifungal activities. Compound 1 also inhibited cytotoxicity to the hepG2 cell line with an IC50 value of 10.0 mu g/mL.

• 出版日期2007-7
• 单位中山大学