A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy

作者：Devisetty Kiran; Mell Loren K; Salama Joseph K; Schomas David A; Miller Robert C; Jani Ashesh B; Roeske John C; Aydogan Bulent; Chmura Steven J^*

来源：Radiotherapy and Oncology, 2009, 93(2): 298-301.

DOI：10.1016/j.radonc.2009.07.006

• Anal cancer
• IMRT
• Chemoradiotherapy
• Gastrointestinal toxicity
• Dosimetric analysis

Using previous dosimetric analysis methods, we identified the volume of bowel receiving 30 Gy (V(30)) correlated with acute gastrointestinal (GI) toxicity in anal cancer patients treated with intensity-modulated radiation therapy and concurrent chemotherapy. For V(30) > 450 cc and <= 450 cc, acute GI toxicity was 33% and 8%, respectively (p = 0.003).

• 出版日期2009-11