Asthma in the elderly

作者：Robitaille C; Boulet L P^*

来源：Revue des Maladies Respiratoires, 2014, 31(6): 478-487.

DOI：10.1016/j.rmr.2014.03.001

• Asthma
• Elderly
• Asthma phenotype
• Geriatric asthma
• Airway inflammation

Asthma is a common condition in the elderly although often confounded with chronic obstructive pulmonary disease (COPD) in this population. Asthma in the elderly seems to represent a specific phenotype characterized by more severe, but often less perceived, airway obstruction, a neutrophilic or mixed-type of airway inflammation and frequent comorbidities. Patients aged 65 years and over have an increased asthma-related morbidity and mortality compared to younger patients, probably due to difficulties in regard to diagnosis, assessment of the disease severity and treatment. Research is urgently needed to determine the optimal treatment of the aged patient. In this document we will review the state of knowledge on this topic and discuss the challenges of multidisciplinary asthma management in the elderly.

• 出版日期2014-6