Controllable porosity conversion of metal-organic frameworks composed of natural ingredients for drug delivery

作者：Liu, Jiang; Bao, Tian-Yi; Yang, Xi-Ya; Zhu, Pei-Pei; Wu, Lian-He; Sha, Jing-Quan^*; Zhang, Lei; Dong, Long-Zhang; Cao, Xue-Li; Lan, Ya-Qian^*

来源：Chemical communications, 2017, 53(55): 7804-7807.

DOI：10.1039/c7cc03673f

• CYCLODEXTRIN INCLUSION-COMPOUNDS
• BETA-CYCLODEXTRIN
• ALPHA-CYCLODEXTRIN
• MOLECULAR COMPOSITE
• SPHERE COORDINATION
• COMPLEXES
• MOF
• CHEMISTRY
• PRODUCTS
• CHLORIDE

Two extremely rare b-cyclodextrin (b-CD) supported metal-organic frameworks (MOFs), CD-MOF-1 and CD-MOF-2, were induced to crystallize for the first time through a template-induced approach. The targeted CD-MOFs were employed to perform controlled drug delivery and cytotoxicity assays that confirmed their favourable biological potential of being used as drug carriers.

• 出版日期2017-7-14
• 单位南京师范大学; 吉林大学; 山东大学; 佳木斯大学; 济宁学院