Nanofiltration removal of pharmaceutically active compounds

作者：Jose Lopez Munoz Maria; Sotto Arcadio; Arsuaga Jesus M^*

来源：Desalination and Water Treatment, 2012, 42(1-3): 138-143.

DOI：10.5004/dwt.2012.2473

• Nanofiltration
• Pharmaceutical
• Water treatment
• Sulfamethoxazole
• Diclofenac
• Hydrochlorothiazide
• 4-Acetamidoautipyrine
• Nictoine
• Ranitidine

Capability of nanofiltration membranes (NF) to remove pharmaceutical active compounds from wastewater streams was investigated. Sulfamethoxazole, diclofenac sodium, hydrochlorothiazide, 4-acetamidoantipyrine, nicotine and ranitinide hydrochloride were selected as model compounds since they are widely produced as pharmaceutical agents. Two commercially available polyamide nanofiltration membranes (NF-90 and NF-270 from Dow FilmTec) were tested. Solute retention by NF-90 membrane was very high in all cases (over 95%), whereas NF-270 retention systematically appeared lower ranging from 75% (nicotine) to 95% (ranitidine hydrochloride). Temporal evolution of flux decline was also investigated. The influence of physicochemical properties of both membrane and solutes on membrane performance was analyzed to explore the main solute-membrane interactions that determine the solute transfer across the membrane. The influence of operation pressure on NF-90 and NF-270 rejection was also studied.

• 出版日期2012-4