A novel magnetically recyclable silver-loaded cellulose-based bionanocomposite catalyst for green synthesis of tetrazolo[1,5-a]pyrimidines

作者：Maleki Ali^*; Ravaghi Parisa; Aghaei Morteza; Movahed Hamed

来源：Research on Chemical Intermediates, 2017, 43(10): 5485-5494.

DOI：10.1007/s11164-017-2941-4

• Cellulose/Fe2O3/Ag bionanostructure
• Magnetic nanocatalyst
• Tetrazole
• NaN3
• Multicomponent reaction

5-Methyl-7-aryl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylic ester derivatives were efficiently synthesized by reaction of methyl or ethyl acetoacetate, 5-aminotetrazole (produced from 2-cyanoguanidine and sodium azide), and various aromatic aldehydes in presence of a new cellulose-based Ag-loaded magnetic bionanostructure. This protocol offers many advantages such as short reaction time, high yield, the remarkable magnetic property of the nanocomposite, and easy separation of the nanocatalyst from the reaction mixture without considerable loss of catalytic activity. Furthermore, X-ray diffraction analysis, field-emission scanning electron microscopy, and energy-dispersive X-ray (EDX) analysis were used to characterize the prepared nanocatalyst.

• 出版日期2017-10