Morphological Changes in Bird Viscera in Experimental Infection by Highly Pathogenic H5N1 Avian Influenza Virus

作者：Shestopalova L V^*; Shkurupiy V A; Sharkova T V; Shestopalov A M

来源：Bulletin of Experimental Biology and Medicine, 2008, 146(6): 770-773.

DOI：10.1007/s10517-009-0376-7

• avian influenza
• H5N1 subtype
• chicken
• pathogenesis
• pathomorphology

Intravenous infection of chicken with H5N1 avian influenza virus (strain A/Gs/Krasnoozerskoye/627/05) causes rapid lethal outcome. Pathomorphological study of bird viscera showed manifestations of disseminated intravascular coagulation syndrome, generalized inflammatory reaction, and wide-scale necrobiotic changes in tissues.

• 出版日期2008-12