An approximation to familial colorectal cancer

作者:Adan Luisa; Alvarez Castro Ana; Castells Antoni*
来源:Gastroenterologia y Hepatologia, 2010, 33(9): 652-659.
DOI:10.1016/j.gastrohep.2009.11.012

摘要

Colorectal cancer is one of the most common neoplasms in western countries and is a worldwide public health problem. A substantial number of cases show familial aggregation of the disease, termed familial colorectal cancer to distinguish it from well-established hereditary forms. The present review discusses current knowledge of the underlying genetic causes, the most appropriate screening strategies and the potential prognostic implications of this entity.

  • 出版日期2010-11