Adaptive designs for Phase I dose-finding studies

作者：Zhou Yinghui^*

来源：Fundamental & Clinical Pharmacology, 2010, 24(2): 129-138.

DOI：10.1111/j.1472-8206.2009.00746.x

• adaptive designs
• Bayesian approaches
• dose-finding studies

Improving methodology for Phase I dose-finding studies is currently of great interest in pharmaceutical and medical research. This article discusses the current atmosphere and attitude towards adaptive designs and focuses on the influence of Bayesian approaches.

• 出版日期2010-4