Facile Amide Formation via S-Nitrosothioacids

作者：Pan Jia; Devarie Baez Nelmi O; Xian Ming^*

来源：Organic Letters, 2011, 13(5): 1092-1094.

DOI：10.1021/ol1031393

Here we report a novel amide bond formation strategy from simple thioacid and amine starting materials. The reaction is mediated by unstable but very reactive S-nitrosothioacid intermediates. This fast reaction under mild conditions should be useful in synthesis.

• 出版日期2011-3-4