New-onset epilepsy: considerations for initial and follow-up MRI to detect brain tumor

作者：Schucht Philippe; Duffau Hugues^*

来源：Expert Review of Neurotherapeutics, 2011, 11(8): 1107-1110.

DOI：10.1586/ERN.11.80

• awake surgery
• epilepsy
• intraoperative electrical mapping
• low-grade glioma
• MRI

Seizures are often the presenting symptoms of a cerebral tumor and may precede its diagnosis by many years. The article under evaluation searched two large English registries for patients admitted for new-onset epilepsy. The risk of subsequently being diagnosed with a malignant brain tumor was found to be 26-fold higher compared with controls, persisted over many years and was accentuated in young patients. Recently, surgical advances have led to a significant decrease in surgical morbidities, making surgery the first treatment option for gliomas, especially low-grade gliomas. This paradigm shift warrants a consequent diagnostic workup (MRI) in patients at risk for low-grade glioma that is, patients with new-onset epilepsy. The study is discussed in the context of the ongoing debate on neuroimaging after new-onset epilepsy.

• 出版日期2011-8