科研之友
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摘要
A facile, green, and one-pot approach is described for the regioselective synthesis of new substituted 3-methyl-6-arylpyridazine-4-carboxamides in water at room temperature. Subsequent treatment of these products with the Vilsmeier reagent led to chemoselective and regioselective production of new 5-oxo-3-aryl-5,6-dihydropyrido[4,3-c]pyridazine-8-carbaldehydes in good to excellent yields.
- 出版日期2018-3
