Does Obesity Affect Outcomes After Decompressive Surgery for Lumbar Spinal Stenosis? A Multicenter, Observational, Registry-Based Study

作者：Giannadakis Charalampis^*; Nerland Ulf S; Solheim Ole; Jakola Asgeir S; Gulati Michel; Weber Clemens; Nygaard Oystein P; Solberg Tore K; Gulati Sasha

来源：World Neurosurgery, 2015, 84(5): 1227-1234.

DOI：10.1016/j.wneu.2015.06.020

• Neurosurgical procedures
• Obesity
• Quality of life
• Spinal stenosis
• Spondylosis

OBJECTIVE: To evaluate the association between obesity and outcomes 1 year after laminectomy or micro-decompression for lumbar spinal stenosis (LSS).
METHODS: The primary outcome measure was the Oswestry Disability Index (ODI). Obesity was defined as body mass index (BMI) >= 30. Prospective data were retrieved from the Norwegian Registry for Spine Surgery.
RESULTS: For all patients (n = 1473) the mean improvement in ODI at 1 year was 16.7 points (95% CI 15.7-17.7, P < 0.001). The improvement in ODI was 17.5 points in nonobese and 14.3 points in obese patients (P=0.007). Obese patients were less likely to achieve a minimal clinically important difference in ODI (defined as >= 8 points improvement) than nonobese patients (62.2 vs. 70.3%, P = 0.013). Obesity was identified as a negative predictor for ODI improvement in a multiple regression analysis (P < 0.001). Nonobese patients experienced more improvement in both back pain (0.7 points, P = 0.002) and leg pain (0.8 points, P = 0.001) measured by numeric rating scales. Duration of surgery was shorter for nonobese patients for both single- (79 vs. 89 minutes, P = 0.001) and 2-level (102 vs. 114 minutes, P = 0.004) surgery. There was no difference in complication rates (10.4% vs. 10.8%, P = 0.84). There was no difference in length of hospital stays for single-(2.7 vs. 3.0 days, P = 0.229) or 2-level (3.5 vs. 3.6 days, P = 0.704) surgery.
CONCLUSIONS: Both nonobese and obese patients report considerable clinical improvement 1 year after surgery for LSS, but improvement was less in obese patients. Obese patients were less likely to achieve a minimal clinically important difference.

• 出版日期2015-11