Bilateral Optic Pathway Ganglioglioma: The Fifth Case in the Literature

作者：Karaaslan Burak^*; Ucar Murat; Kulduk Gamze; Borcek Alp Ozgun; Baykaner M Kemali

来源：Pediatric Neurosurgery, 2016, 51(1): 48-54.

DOI：10.1159/000439541

• Ganglioglioma
• Optic tract
• Visual field defect
• Suprasellar tumor
• Histopathology

Gangliogliomas are mixed tumors which contain both glial and neuronal elements. The optic pathway is a very rare location for gangliogliomas, with less than 23 cases reported in the literature. Bilateral involvement of the entire optic pathway was reported in only 4 cases before. Because of similar radiological appearance of other pathological entities such as gliomas and craniopharyngiomas, histopathological diagnosis is essential. We report a ganglioglioma case that involved both optic pathways. A 12-year-old patient suffering from visual deterioration for 6 months was evaluated. After a visual field test and radiological examinations, a microsurgical biopsy procedure was performed. Pathological examination revealed dysplastic/neoplastic ganglion cells and neoplastic glial cells, and the diagnosis was a World Health Organization (WHO) grade 1 ganglioglioma. The patient is scheduled for adjuvant radiotherapy with the hope of prevention of progression.

• 出版日期2016