A facile one-pot synthesis of dicycloalkenopyridines at ambient temperature conditions

作者：Goswami Santosh V; Thorat Prashant B; Bhusare Sudhakar R^*

来源：Tetrahedron Letters, 2012, 53(50): 6771-6774.

DOI：10.1016/j.tetlet.2012.09.134

• Dicycloalkenopyridines
• Aromatic aldehyde
• Cyclohexanone
• Hydroxylamine hydrochloride
• 3-Nitrophenylboronic acid

An efficient synthesis of dicycloalkenopyridines was achieved via one-pot three-component condensation of aromatic aldehyde, cyclohexanone, and hydroxylamine hydrochloride using 3-nitrophenylboronic acid as an efficient catalyst under ambient condition. The current methodology offers several advantages such as high yields (78-90%) and simple experimental work-up at ambient temperature conditions.

• 出版日期2012-12-12