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摘要
The objective of this research was to develop and validate an alternative analytical method for quantitative determination of levofloxacin in tablets and injection preparations. The calibration curves were linear over a concentration range from 3.0 to 8.0 mu g mL(-1). The relative standard deviation was below 1.0% for both formulations and average recovery was 101.42 +/- 0.45% and 100.34 +/- 0.85% for tablets and injection formulations, respectively. The limit of detection and limit of quantitation were 0.08 and 0.25 mu g mL(-1), respectively. It was concluded that the developed method is suitable for the quality control of levofloxacin in pharmaceuticals formulations.
- 出版日期2010
