Annealing regulates the performance of an electrospun poly(epsilon-caprolactone) membrane to accommodate tissue engineering

作者：Zhang, Jin; Liu, He; Ding, Jian-Xun^*; Zhuang, Xiu-Li; Chen, Xue-Si; Li, Zhong-Ming

来源：RSC Advances, 2015, 5(41): 32604-32608.

DOI：10.1039/c5ra05530j

• MECHANICAL-PROPERTIES
• SCAFFOLDS
• STABILITY

The profound effect of annealing on the electrospun poly(epsilon-caprolactone) scaffold is comprehensively investigated for the first time. Interestingly, after annealing at 42 degrees C, the contact angle of the sample decreases from (133.39 +/- 3.20) to (124.11 +/- 2.08)degrees, meanwhile the Young's modulus dramatically increases from 8.41 +/- 1.64 to 11.27 +/- 2.41 MPa, which is attributed to the improved crystallinity. The above results and additional excellent cellular proliferation demonstrate that the annealed matrix possesses better physical and biological performances as a tissue engineering scaffold.

• 出版日期2015
• 单位吉林大学; 中国科学院; 中国科学院长春应用化学研究所; 高分子材料工程国家重点实验室; 四川大学