Mucinous cystadenocarcinoma of the testis: a case report

作者：Iuga Alina Cornelia^*; Mull Jason; Batra Rashmi; Miller William

来源：Human Pathology, 2011, 42(9): 1343-1347.

DOI：10.1016/j.humpath.2010.11.021

• Mucinous
• Cystadenocarcinoma
• Testis
• Intratesticular
• Cyst
• Intestinal
• Ovarian surface epithelial tumor
• Testicular adenocarcinoma

We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet and ciliated cells completely replacing the testicular parenchyma. Immunohistochemical studies showed positivity for cytokeratin 20, carcinoembryonic antigen, and mucin 2, and negativity for cytokeratin 7, mucin SAC, vimentin, thyroid transcription factor 1, Wilms' tumor 1, and cancer antigen 125. The current case shows a focal cyst-lining component with benign appearance. Imaging studies and colonoscopy showed no evidence of other suspicious lesions. This tumor resembles morphologically to an intestinal-type ovarian surface epithelial tumor.

• 出版日期2011-9