摘要
Some novel triazolo[1,5-a]pyridine (4-6), thiazolo[3,2-a]pyridine (7), thiazolo[3,2-a]pyrimidines (9, 11), oxoimidazo[1,2-a]pyrimidine (10), and pyrimido[2,1-b]quinazoline (12) have been synthesized. The structures of target compounds were confirmed by elemental analyses and spectral data. The antimicrobial activity of some of the target synthesized compounds were tested against various microorganisms such as Salmonella typhimurium, Pseudomonas aeruginos and Staphylococcus aureus (bacteria), Aspergillus flavus (fungus), and Candida albicans (yeast fungus) by the disc diffusion method. In general, the novel synthesized compounds showed a good antimicrobial activity against these microorganisms.
- 出版日期2015-4