A study of detection rate and colonoscopic information in 5130 colorectal polyps

作者:Liu, Lan; Gao, Hongwei; Wu, Honglei; Chen, Zhaosheng; Teng, Guoxin; Guo, Jianqiang*
来源:International Journal of Clinical and Experimental Medicine, 2016, 9(7): 14369-14375.

摘要

Objective: This study aims to help physicians obtain the detection rate and colonoscopic information of colorectal polyps and define the risk profile of neoplastic polyps at a main hospital in China. Method: A total of 15,189 participants who underwent total colonoscopy between January 2000 and September 2015 were studied. A total of 5,130 colorectal polyps were diagnosed. We analyzed the detection rate, anatomical sites, and pathological types among different sex, age, and decade groups. Moreover, we investigated the relationships of anatomical sites vs. pathological types and adenoma vs. adenocarcinoma. Results: Colonoscopic examinations revealed that women demonstrated a lower risk for colorectal polyps (27.75% vs. 38.56%; P=0.000), and detection rate significantly increased with age and decade (by age, 17.04% vs. 40.10% vs. 49.99%; by decade, 13.99% vs. 52.07%; P=0.000). Polyps located mostly in the rectum, and which located in the transverse and ascending colon increased with age. The most common polyp pathology was adenoma, and its proportion in the old-aged group was significantly higher than that in the other groups (51.48% vs. 59.85% vs. 71.53%; P=0.000). A significant difference was observed between adenoma and adenocarcinoma in anatomical sites (P=0.000). Compared with adenoma, adenocarcinoma was more frequently located in the rectum (20.02% vs. 48.75%; P=0.000). Conclusion: Adenoma is more prevalent in high-risk groups for cancer, including old-aged group and men. Therefore, male and old-aged groups may benefit more from colonoscopy in our population than other groups. Adenoma located in the rectum may have a high malignant tendency. Thus, digital rectal examination should be given priority.