NbCl5 as an Efficient Catalyst for the Synthesis of 1,5-Benzodiazepine Derivatives

作者：Gao Shu Tao; Liu Wei Hua; Ma Jing Jun; Wang Chun^*; Liang Qian

来源：Synthetic Communications, 2009, 39(18): 3278-3284.

DOI：10.1080/00397910902752238

• 1
• 5-Benzodiazepines
• ketones
• NbCl5
• o-phenylenediamines

1,5-Benzodiazepine derivatives were synthesized in moderate to excellent isolated yields by the condensation reactions of o-phenylenediamine and ketones catalyzed by NbCl5 under mild conditions using n-hexane as solvent at 50 degrees C. This method is simple and effective with good yields.

• 出版日期2009
• 单位河北农业大学