Diterpenes with Unprecedented Skeletons from the Red Alga Sphaerococcus coronopifolius

作者:Smyrniotopoulos Vangelis; Kiss Robert; Mathieu Veronique; Vagias Constantinos; Roussis Vassilios*
来源:European Journal of Organic Chemistry, 2015, 2015(13): 2848-2853.
DOI:10.1002/ejoc.201500133

摘要

Three previously unknown diterpenes - spirosphaerol (1), anthrasphaerol (2) and corfusphaeroxide (3) - have been isolated from the red alga Sphaerococcus coronopifolius. Their structures were elucidated by spectral analysis, including NMR and MS. The isolated metabolites were evaluated for their in vitro antitumour activities against one murine and five human cancer cell lines.

  • 出版日期2015-5