Associations of blood pressure, sunlight, and vitamin D in community-dwelling adults

作者：Rostand Stephen G^*; McClure Leslie A; Kent Shia T; Judd Suzanne E; Gutierrez Orlando M

来源：Journal of Hypertension, 2016, 34(9): 1704-1710.

DOI：10.1097/HJH.0000000000001018

• blood pressure
• hypertension
• season
• solar insolation
• sunshine
• vitamin D

Background: Vitamin D deficiency/insufficiency is associated with hypertension. Blood pressure (BP) and circulating vitamin D concentrations vary with the seasons and distance from the equator suggesting BP varies inversely with the sunshine available (insolation) for cutaneous vitamin D photosynthesis.
Methods: To determine if the association between insolation and BP is partly explained by vitamin D, we evaluated 1104 participants in the Reasons for Racial and Geographic Differences in Stroke study whose BP and plasma 25-hydroxyvitamin D [25(OH)D] concentrations were measured.
Results: We found a significant inverse association between SBP and 25(OH) D concentration and an inverse association between insolation and BP in unadjusted analyses. After adjusting for other confounding variables, the association of solar insolation and BP was augmented, 0.3.5 +/- SEM 0.01 mmHg/1 SD higher solar insolation, P = 0.01. The greatest of effects of insolation on SBP were observed in whites (-5.2 +/- SEM 0.92 mmHg/1 SD higher solar insolation, P = 0.005) and in women (-3.8 +/- SEM 1.7 mmHg, P = 0.024). We found that adjusting for 25(OH)D had no effect on the association of solar insolation with SBP.
Conclusion: We conclude that although 25(OH)D concentration is inversely associated with SBP, it did not explain the association of greater sunlight exposure with lower BP.

• 出版日期2016-9