A novel electrocatalyst with high sensitivity in detecting glutathione reduced by 2-hydroxypropyl-beta-cyclodextrin enveloped 10-methylphenothiazine

作者:Li Xueni*; Zheng Longzhen; Wang Yimin; Zhang Nan; Lou Yan; Xiao Ting; Liu Jiani
来源:RSC Advances, 2015, 5(88): 71749-71755.
DOI:10.1039/c5ra08356g

摘要

This paper reports on an experimental research of a 2-hydroxypropyl-b-cyclodextrin (HP-beta-CD) enveloped 10-methylphenothiazine (MPT) catalyst (MPT-HP-beta-CD) with high sensitivity and wonderful electrical conductivity for the electrochemical detection of reduced glutathione (GSH) in a neutral environment. We obtained a linear response range from 10(-6) mol L-1 to 5.8 x 10(-4) mol L-1 for GSH with a low detection limit of 2.87 x 10(-7) mol L-1, providing a potentially usefulness in the development of sensors for non-enzyme detection of GSH.

  • 出版日期2015