An efficient synthesis of 1 alpha,25-dihydroxy-20-epi-vitamin D-3

作者：Fraga R; Lopez Perez B; Sokolowska K; Guini A; Regueira T; Diaz S; Mourino A; Maestro M A^*

来源：Journal of Steroid Biochemistry and Molecular Biology, 2013, 136: 14-16.

DOI：10.1016/j.jsbmb.2013.01.010

• Vitamin D analogues synthesis
• 1 alpha,25-Dihydroxy-20-epi-vitamin D-3
• MC1288
• Palladium(0)-catalyzed coupling

The synthesis of 1 alpha,25-dihydroxy-20-epi-vitamin D-3 (1) by Pd(0)-catalyzed coupling between the boronate ester (2) and the enol triflate (3) is described. %26lt;br%26gt;This article is part of a Special Issue entitled %26apos;Vitamin D Workshop%26apos;.

• 出版日期2013-7