Magnetic and inductive heating properties of Fe3O4/polyethylene glycol composite nanoparticles with core-shell structure

作者：Zhao, Dong-Lin^*; Teng, Pan; Xu, Ying; Xia, Qi-Sheng; Tang, Jin-Tian

来源：Journal of Alloys and Compounds, 2010, 502(2): 392-395.

DOI：10.1016/j.jallcom.2010.04.177

• Nanostructures
• Nanofabrications
• Scanning and transmission electron microscopy
• X-ray diffraction
• Magnetic measurements

The magnetite (Fe3O4) nanoparticles were prepared by coprecipitation of Fe3+ and Fe2+ using ammonium hydroxide (NH4OH) as a precipitating agent. The Fe3O4/polyethylene glycol (PEG) magnetic composite nanoparticles with a core-shell structure with a diameter of 10-40 nm were prepared by two step additions of the primary and the secondary surfactants, respectively. The inductive heat property of Fe3O4/PEG composite nanoparticles in an alternating current (AC) magnetic field was investigated. The potential of Fe3O4/PEG nanoparticles was evaluated for localized hyperthermia treatment of cancers. The saturation magnetization, Ms, and coercivity, Hc, are 67.06 emu g(-1) and 7 Oe for Fe3O4 nanoparticles and 64.11 emu g(-1) and 14 Oe for Fe3O4/PEG composite nanoparticles, respectively. Exposed in the AC magnetic field for 100 s, the temperatures of physiological saline suspensions containing Fe3O4 nanoparticles or Fe3O4/PEG composite nanoparticles are 89.2 degrees C and 72.2 degrees C, respectively. The Fe3O4/PEG composite nanoparticles will be useful as good thermoseeds for localized hyperthermia treatment of cancers.

• 出版日期2010-7-23
• 单位化工资源有效利用国家重点实验室; 清华大学; 中日友好医院; 中山大学; 北京化工大学