An OP4 Functional Stream in the Language-Related Neuroarchitecture

作者：Sepulcre Jorge^*

来源：Cerebral Cortex, 2015, 25(3): 658-666.

DOI：10.1093/cercor/bht256

• auditory-motor (A M) interface
• functional connectivity
• graph theory
• language
• network

Sensory comprehension and motor production of language symbols form the basis of human speech. Classical neuroanatomy has pointed to Wernicke's and Broca's areas as playing important roles in the integration of these 2 functions. However, recent studies have proposed that more direct pathways may exist between auditory input and motor output, bypassing Wernicke's and Broca's areas. We used functional network analyses to investigate potential auditorymotor (A-M) couplings between language-related cortices. We found that operculum parietale (OP) interconnectivity in region OP-4 seems to play a critical role in the A-M integration of the brain. This finding supports a novel landscape in the functional neuroarchitecture that sustains language in humans.

• 出版日期2015-3