Anomalous phosphenes in ocular protontherapy

作者：Khan E^*; Marechal F; Dendale R; Mabit C; Calugaru V; Desjardin L; Narici L

来源：Advances in Space Research, 2010, 45(7): 846-849.

DOI：10.1016/j.asr.2009.11.021

• Protons
• Phosphenes
• Light flashes
• ALTEA

We have undertaken a clinical ground study of proton-induced light flashes (phosphenes). Patients treated at the Instiiut Curie - Centre de Protontherapie in Orsay, France, received radiation therapy to cure ocular and skull-base cancers. Sixty percent of the patients treated for choroidal melanomas using 73 MeV protons report anomalous phosphenes. Delivering a radiation dose on the retina only is not sufficient to trigger the light flash. The present study may be the first indication of phosphenes triggered by protons of few tens of MeV.

• 出版日期2010-4-1